Parasail with Diluent

Haemophilus parasuis is an early colonizer of the upper respiratory tract of pigs1. Virulent

strains of H. parasuis can invade the host and cause systemic lesions characterized by

fibrinous polyserositis, arthritis, and meningitis.1 H. parasuis primarily affects young pigs

4-8 weeks of age but sporadic disease can be observed in adult pigs.1 Disease caused by

H. parasuis has a sudden onset, short course and high morbidity and mortality rates.1

Clinical Signs1

Clinical signs are seen primarily in pigs 4-8 weeks old and include:

• High fever (106.7ºF) • Swollen joints

• Lack of appetite • Reluctance to rise

• Severe coughing • Paddling

• Abdominal breathing • Trembling

PARASAIL H. parasuis vaccine was administered to 1,068 pigs at approximately 3 weeks

of age. Just 0.66% displayed adverse systemic reactions; all of which recovered within a

few minutes. Injection site swelling was observed in 6.6% of pigs 7 days post vaccination.

Only one pig (0.095%) displayed injection site swelling 21 days post vaccination.

PARASAIL safety has been documented with field safety studies as well as USDArequired

studies to determine if post-vaccination shedding or spread to non-vaccinates

occurs. Neither occurred. Also, reversion to virulence was shown not to occur with a

USDA-required back-passage study.

PARASAIL Performance4

In field trials, PARASAIL reduced lesions associated with H. parasuisby 50%. In the same trial, PARASAIL reduced arthritis by 86%.

PARASAIL Features5

• Avirulent live H. parasuis protection

• Single dose - reduces time, handling and animal stress

• Low 1mL dose volume - Low tissue disruption & excellent syringeability

• 21-day withdrawal period

Mixing Directions

Aseptically rehydrate freeze-dried vial of PARASAIL with part of the accompanying bottle of diluent

(see insert for complete directions). Mix reconstituted vial well and transfer rehydrated vaccine into

diluent bottle. Shake diluent bottle well. Peel label from freeze-dried vial and place on diluent bottle

containing all vaccine.

Caution

Discontinue antibiotic therapy 72 hours before vaccination, do not resume until 24 hours post

vaccination. Store refrigerated at 35º - 45º F (2º - 7ºC). Do not freeze. Use immediately after

reconstitution; do not save partial contents. Burn the container and all unused contents. Do not

vaccinate within 21 days before slaughter. Transient reaction may occur at injection site. If anaphylaxis

occurs, use epinephrine or equivalent. Contains Streptomycin and Amphotericin B as preservatives.